HLA DRA Antibody (169-1B5.2), PE/Cy5.5, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-47722PECY55

Product Code. 18195149

Description

HLA DRA Monoclonal specifically detects HLA DRA in Human, Bovine, Feline samples. It is validated for Flow Cytometry.

Specifications

• Antigen: HLA DRA
• Classification: Monoclonal
• Conjugate: PE-Cyanine5.5
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: HLA-DRA
• Immunogen: Human peripheral blood leukocytes (Uniprot: P01903)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: 169-1B5.2
• Dilution: Flow Cytometry
• Gene Alias: FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
• Gene ID (Entrez): 3122.0
• Target Species: Human, Bovine, Feline
• Isotype: IgG2b κ