HJURP Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA552562

Product Code. 15760511

Description

Immunogen sequence: TPVVQMATLT YETPQGLRIW GGRLIKERNE GEIQDSSMKP ADRTDGSVQA AAWGPELPSH RTVLGADSKS GEVDATSDQE ESVAWALAPA VPQSPLKNEL RRKYLTQVDI LLQGAEYFEC AGNRAGRDVR V Highest antigen sequence identity to the following orthologs: Mouse - 37%, Rat - 43%.

Centromeric protein that plays a central role in the incorporation and maintece of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.

Specifications

• Antigen: HJURP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HJURP
• Gene Alias: Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9, HJURP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55355
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NCD3
• Gene Symbols: HJURP
• Immunogen: Recombit protein corresponding to Human HJURP
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

Research Use Only