Cytiva HiTrap™ MabSelect™ Prepacked Columns

Product Code.	Quantity	Product Line	Unit Size
11793319	1 x 5 mL	MabSelect™ Xtra	Each
11783319	1 x 5 mL	MabSelect	Each
10106234	5 x 1 mL	MabSelect™ Xtra	Pack of 5
11550634	5 x 5 mL	MabSelect™ Xtra	Pack of 5
11545135	5 x 5 mL	MabSelect	Pack of 5
10359534	5 x 1 mL	MabSelect	Pack of 5

Product Code. 11793319 Supplier Cytiva Supplier No. 28408260

Descrizione

Use these columns in small-scale MAb purification in a continuous bioprocess. Cytiva Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes

Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.

• Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
• High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
• Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
• Designed for use with a syringe, a peristaltic pump, or a chromatography system

MabSelect

• Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
• Recombinant Protein A ligand promotes specificity of binding to F_c region of IgG; permits one-step purification

MabSelect Xtra™

• Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
• Allows binding from samples with high expression levels of the monoclonal antibody
• Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches

MabSelect SuRe™ (Superior Resistance)

• Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
• Permits significant cost savings and extension of cycles in regular production

Specifica

• Product Line: MabSelect™ Xtra
• Binding Capacity: ∼40 mg/mL Human lgG at 2.4 min. residence time
• Diameter (Metric) Inner Column: 1.6 cm
• Diameter (English) Inner Column: 0.62 in.
• Flow Rate: <4 mL/min.
• Volume (Metric) Bed: 5 mL
• For Use With (Application): For fast purification of monoclonal antibodies from large sample volumes, Protein Purification
• Sample Volume: 5 mL
• Storage Buffer: 20% Ethanol
• Content And Storage: 4°C to 30°C
• Quantity: 1 x 5 mL

Sicurezza e movimentazione

Identificativo prodotto

• HiTrap MabSelect Xtra, 5 ml, 1 x 5 ml

Avvertenza

• Warning

Categoria di pericolo

• Flammable liquid Category 3

Indicazioni di pericolo

• H226-Flammable liquid and vapour.

Consigli di prudenza

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Informazioni supplementari

• MIXTURE LIST-Contain: ethanol