Cytiva HiTrap™ Capto™ MMC ImpRes Column

Product Code. 16360906

Brand: Cytiva 29401108

Description

Prepacked with a weak cation exchange multimodal resin for screening and small-scale purifications

• The multimodal functionality of Capto MMC ImpRes offers a different selectivity compared to traditional ion exchange columns
• Binds proteins at high or low ionic strength
• Efficiently removes contaminants such as DNA, host cell proteins (HCP), leached protein A, and aggregates
• An excellent choice for purification of MAbs and other biomolecules with high aggregate content.
• Can typically be used in the initial polishing step in MAb purification processes, as well as for polishing of antibody fragments such as domain antibodies (DAbs)
• High yields achieved through the high-resolution beads and selectivity of the ligand
• Enables use of a platform approach to MAb process development
• Displays a broad pH/salt operational window
• Ideal for screening of selectivity, binding, and elution conditions, as well as for small scale purifications

Specifications

• Description: High-Resolution Polishing of Monoclonal Antibodies (MAbs) and Other Biomolecules
• Matrix: High-Flow Agarose
• Flow Rate: <4 mL/min
• For Use With (Application): Multimodal Ion Exchange Chromatography
• Ligand Type: Multimodal Weak Cation Exchanger
• Content And Storage: Store at 4°C to 30°C in 20% Ethanol, 0.2 M Sodium Acetate
• Binding Strength: 60 to 90 mg MAb/mL
• Max. Operating Pressure: 5 bar (70 psi)
• Column Type: Pre-packed Column
• Diameter (Metric) Inner Column: 7 mm
• Volume (Metric): 1 mL
• pH: 3 to 12
• Quantity: 1 Ea.
• Length (Metric): 25 mm

Safety and Handling

Product Identifier

• HiTrap Capto MMC ImpRes, 1 x 1 ml

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3

Hazard Statement

• H226-Flammable liquid and vapour.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : ethanol
• UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.