Histone H3.3 Rabbit, Clone: RM190, Abnova™

Rabbit monoclonal antibody raised against synthetic peptide of human Histone H3.3.

Brand:  Abnova MAB12805.100ug

Product Code. 16148869

Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq]

Specifications

• Antigen: Histone H3.3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (0.2 ug/mL-1 ug/mL) Western Blot (0.5 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: H3.3A/H3F3/MGC87782/MGC87783
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 3020
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: RM190
• Description: Rabbit monoclonal antibody raised against synthetic peptide of human Histone H3.3.
• Formulation: In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
• Gene Symbols: H3F3A
• Immunogen: A synthetic peptide corresponding to Histone H3.3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts to Histone H3.3, independent of post-translational modifications. No cross reactivity with Histone H3.1 or other histone proteins.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG