Invitrogen™ Histone H2B Biosimilar Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA558944

Product Code. 30284293

Description

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term Immunomedics patent anti-Histone H2B.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

Specifications

• Antigen: Histone H2B Biosimilar
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Host Species: Human
• Quantity: 1 mg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
• Concentration: 1 mg/mL
• Formulation: 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1