HIF3A Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 27650-1-AP-20UL

Product Code. 16805765

Description

Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (also designated Arnt 1), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.

Specifications

• Antigen: HIF3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HIF3A
• Gene Alias: bHLHe17, HIF 3 alpha, HIF 3A, HIF 3A2, HIF 3A4, HIF3 alpha, HIF3 alpha 1, HIF3A, Inhibitory PAS domain protein, IPAS, Member of PAS protein 7, MOP7, PASD7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64344
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Western Blot, Immunocytochemistry
• Concentration: 0.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9Y2N7
• Gene Symbols: HIF3A
• Immunogen: HIF3A Fusion Protein Ag26574
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG