Invitrogen™ HFE Recombinant Rabbit Monoclonal Antibody (2O7D2)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA542637

Product Code. 17749243

Description

Positive test controls include: HeLa, HT-29, A-549. The target is usually found in the following locations: Cell membrane, Single-pass type I membrane protein. Immunogen sequence: KEFEPKDVLP NGDGTYQGWI TLAVPPGEEQ RYTCQVEHPG LDQPLIVIWE PSPSGTLVIG VISGIAVFVV ILFIGILFII LRKRQGSRGA MGHYVLAERE.

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin. It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Specifications

• Antigen: HFE
• Classification: Recombinant Monoclonal
• Concentration: 0.6 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q30201
• Gene Symbols: HFE
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 2O7D2
• Conjugate: Unconjugated
• Gene: HFE
• Gene Alias: hemochromatosis; hereditary hemochromatosis protein; hereditary hemochromatosis protein HLA-H; hereditary hemochromatosis protein homolog; Hfe; HFE 1; HFE1; HH; high Fe; HLA H; HLAH; HLA-H; MGC:150812; MGC10379; MGC103790; MHC class I-like protein HFE; Mr2; MVCD7; RT1-CAFE; TFQTL2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3077
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid