Invitrogen™ HFE Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102408

Product Code. 16628884

Description

Antibody detects endogenous levels of total HFE.

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin. It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Specifications

• Antigen: HFE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HFE
• Gene Alias: hemochromatosis; hereditary hemochromatosis protein; hereditary hemochromatosis protein HLA-H; hereditary hemochromatosis protein homolog; Hfe; HFE 1; HFE1; HH; high Fe; HLA H; HLAH; HLA-H; MGC:150812; MGC10379; MGC103790; MHC class I-like protein HFE; Mr2; MVCD7; RT1-CAFE; TFQTL2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15216, 29199, 3077
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O35799, P70387, Q30201
• Gene Symbols: HFE
• Immunogen: A synthesized peptide derived from human HFE(Accession Q30201), corresponding to amino acid residues Q119-W169.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG