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Tocris Bioscience™ Hesperadin hydrochloride

Description
ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Prevents chromosome alignment and segregation; also induces polyploidy and prevents histone H3-Ser10 phosphorylation. Overrides the spindle assembly checkpoint and induces mitotic exit in monastrol - and taxol -treated HeLa cells.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 553.12 |
| Purity | >99% |
| Molecular Weight (g/mol) | 516.66 |
| Chemical Name or Material | Hesperadin hydrochloride |
Product Title
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