Invitrogen™ Hemoglobin gamma A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA577998

Product Code. 16366704

Description

Positive Control: K562 Predicted Reactivity: Chimpanzee (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon - gamma-G - gamma-A - delta - beta-3'.

Specifications

• Antigen: Hemoglobin gamma A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hbg1
• Gene Alias: A-gamma globin; epsilon 3 globin; gamma A hemoglobin; gamma globin; gamma-1-globin; Hb F Agamma; Hbb-y; Hbe1; Hbg1; HBGA; HBGR; HBG-T2; Hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin subunit gamma 1; hemoglobin subunit gamma-1; hemoglobin Y beta-like embryonic chain; hemoglobin Y, beta-like embryonic chain; hemoglobin, epsilon 1; hemoglobin, gamma A; hemoglobin, gamma, regulator of; HSGGL1; PRO2979
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3047, 94164
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P69891
• Gene Symbols: Hbg1
• Immunogen: Full length human Hemoglobin gamma A Recombinant protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG