Invitrogen™ Hemoglobin alpha-1 Monoclonal Antibody (C5)

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17896922	Invitrogen™ MA541603	200 μL
17674236	Invitrogen™ MA543783	20 μL

Description

Hemoglobin alpha-1 Monoclonal Antibody for Western Blot, IHC (P)

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Specifications

• Antigen: Hemoglobin alpha-1
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P01946, P69905
• Gene ID (Entrez): 25632, 3039
• Immunogen: Recombinant protein Hemoglobin Alpha 1. The antigen corresponds to amino acid range 1-142 of the target protein.
• Product Type: Antibody

• Clone: C5
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1 κ
• Target Species: Human, Rat
• Gene: HBA1
• Gene Alias: alpha one globin; alpha-2 globin chain; Alpha-globin; delta globin; HBA1; HBA2; HBA-T3; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1
• Gene Symbols: HBA1
• Primary or Secondary: Primary
• Purification Method: Protein A/G