Heme oxygenase 2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA577832

Product Code. 16376544

Description

2 μg/mL of PA5-77832 was sufficient for detection of HO-2 in 20 μg of Rat brain lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. ∣Detects approximately 36kDa.

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene.

Specifications

• Antigen: Heme oxygenase 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HMOX2
• Gene Alias: heme oxygenase (decycling) 2; heme oxygenase 2; heme oxygenase-2 non-reducing isoform; HMOX 2; HMOX2; HO 2; HO2; HO-2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 15369, 3163, 79239
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: O70252, P23711, P30519
• Gene Symbols: HMOX2
• Immunogen: Rat native full-length HO-2 purified from testes
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG