Helios Armenian Hamster, PE, Clone: 22F6, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9883-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15557266

Quantity Price
1 £ 229.69 / 100 tests
EU Stock 3
Add to basket

Description and Specification


Primary or Secondary Primary
Antigen Helios
Gene Alias Ikaros family zinc finger 2
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Canine, Human, Mouse
Applications Flow Cytometry (Intracellular Staining)
Quantity 100 tests
Monoclonal or Polyclonal Monoclonal
Conjugate PE
Concentration 5μL (0.03μg)/test
Format Conjugated
Host Species Armenian Hamster
Regulatory Status RUO
Isotype IgG
Clone 22F6

This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and adult mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia.

22F6 has been reported to cross react with rat Helios.