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Invitrogen™ HEC1 Monoclonal Antibody (9G3.23)

Description
Positive control of HELA WCE suggested.
Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
Specifications
Specifications
| Antigen | HEC1 |
| Applications | Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Proximity Ligation Assay, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 9G3.23 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and no preservative |
| Gene | NDC80 |
| Gene Accession No. | O14777, Q9D0F1 |
| Gene Alias | 2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3 |
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