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HDACs/mTOR Inhibitor 1, MedChemExpress

Product Code. 16471087
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Product Code. 16471087

Brand: Medchem Express HY114414

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Description

MedChemExpress HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo.

HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo.

Specifications

Chemical Name or Material HDACs/mTOR Inhibitor 1
CAS 2271413-06-8
Color White
Purity Grade Notes Research
Molecular Formula C28H38N8O5
Quantity 50 mg
Solubility Information DMSO : 32.5 mg/mL (57.35 mM; Need ultrasonic)
SMILES O=C(NO)CCCCCCN1C2=NC(C3=CC=C(NC(N4C[C@@H](C)OCC4)=O)C=C3)=NC(N5CCOCC5)=C2C=N1
Molecular Weight (g/mol) 566.65
Formula Weight 566.65
Percent Purity 98.21%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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