Invitrogen™ HDAC6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595908

Product Code. 16528751

Description

Immunogen sequence: MTSTGQDSTT TRQRRSRQNP QSPPQDSSVT SKRNIKKGAV PRSIPNLAEV KKKGKMKKLG QAMEEDLIVG LQGMDLNLEA EALAGTGLVL DEQLNEFHCL WDDSFPEGPE RLHAIKEQLI QEGLLDRCVS FQARFAEKEE LMLVHSLEYI DLMETTQYMN EGELRVLADT YDSVYLHPNS YSCACLASGS VLRLVDAVLG; Positive Samples: K-562, HeLa; Cellular Location: Cell projection, Cytoplasm, Nucleus, Perikaryon, axon, dendrite.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Specifications

• Antigen: HDAC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HDAC6
• Gene Alias: CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10013, 15185, 84581
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UBN7, Q9Z2V5
• Gene Symbols: HDAC6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HDAC6 (NP_0060352).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG