Invitrogen™ HDAC3 Recombinant Rabbit Monoclonal Antibody (RM439)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA538679

Product Code. 17420993

Description

HDAC3 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

• Antigen: HDAC3
• Classification: Recombinant Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene Accession No.: O15379
• Gene Symbols: HDAC3
• Immunogen: A peptide corresponding to the C-terminous of HDAC3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: RM439
• Conjugate: Unconjugated
• Gene: HDAC3
• Gene Alias: AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8841
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid