HCN3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5111879

Product Code. 17149793

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: (C)QRATGDG SPRRKGSGSE R Homology: Human, mouse amino acid residues are identical.

HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.

Specifications

• Antigen: HCN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hcn3
• Gene Alias: Bcng4; BCNG-4; Hac3; HAC-3; Hcn3; Hcn4; Hyperpolarization-activated cation channel 3; KIAA1535; MGC131493; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114245, 15168, 57657
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.75 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O88705, Q9JKA8, Q9P1Z3
• Gene Symbols: Hcn3
• Immunogen: Peptide corresponding to amino acid residues 727-744 of rat HCN3 (Intracellular, C-terminus)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG