Invitrogen™ hCG beta-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102950

Product Code. 16649404

Description

Antibody detects endogenous levels of total CGB.

The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB2 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017). However, a 163 aa protein, translated from a different frame, is about the same size, and shares 98% identity with other CGB subunits. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: hCG beta-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CGB2
• Gene Alias: CGB2; CGB3; CGB5; CGB7; CGB8; CG-beta; Choriogonadotropin subunit beta variant 2; chorionic gonadotropin beta subunit 2; chorionic gonadotropin human; chorionic gonadotropin, beta polypeptide 2; hCGB; human chorionic gonadotropin; product of CGB2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114336
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6NT52
• Gene Symbols: CGB2
• Immunogen: A synthesized peptide derived from human CGB2(Accession Q6NT52), corresponding to amino acid residues S105-P155.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG