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  5. Tocris Bioscience™ HC 067047

Tocris Bioscience™ HC 067047

Product Code. 18045232
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50 mg
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18045232 50 mg 50mg
18015432 10 mg 10mg
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Product Code. 18045232 Supplier Tocris Bioscience™ Supplier No. 4100/50

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Description

Potent and selective TRPV4 antagonist

HC 067047 is a potent and selective TRPV4 antagonist. Reversibly inhibits currents through mouse, human and rat TRPV4 orthologs (IC50 values are 17, 48 and 133 nM respectively). Also inhibits the endogenous TRPV4-mediated response to 4α-PDH (IC50 = 22 nM). Selective for TRPV4 over TRPV1, TRPV2, TRPV3 and TRPM8 channels.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
CAS 883031-03-6
Quantity 50 mg
Target TRPV Antagonists
Molecular Formula C26H28F3N3O2
Purity 0.99
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