Invitrogen™ HAND2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA564981

Product Code. 15987754

Description

Immunogen sequence: SLVGGFPHHPV VHHEGYPFAA AAAAAAAAAA SRCSHEENPY FHGWLIGHPE MSPPDYSMAL SY Highest antigen sequence identity to the following orthologs - mouse 100%, rat 70%.

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

Specifications

• Antigen: HAND2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAND2
• Gene Alias: AI225906; AI661148; basic helix-loop-helix transcription factor HAND2; bHLHa26; Class A basic helix-loop-helix protein 26; deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2; DHAND; dHAND basic helix-loop-helix transcription factor; dHand protein; DHAND2; Ehand2; han; Hand2; hands off; heart and neural crest derivatives expressed 2; heart and neural crest derivatives expressed transcript 2; heart- and neural crest derivatives-expressed protein 2; Hed; helix-loop-helix transcription factor expressed in embryo and deciduum; Th2; Thing2; thing-2; zdHAND; zgc:103415
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9464
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P61296
• Gene Symbols: HAND2
• Immunogen: Recombinant Human HAND2. Recombinant protein control fragment (Product #RP-104565).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG