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Tocris Bioscience™ GW 0742
Description
Potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 471.49 |
| Purity | >98% |
| Molecular Weight (g/mol) | 471.485 |
| Chemical Name or Material | GW 0742 |
Product Title
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