Guanidine Hydrochloride, Practical Grade, MP Biomedicals

Product Code. 11324359

Brand: MP Biomedicals 02101905.2

Description

• Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins
• This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins
• This can be used as the first step in refolding proteins or enzymes into their active form
• Urea and dithiothreitol (DTT) may also be necessary
• It is also used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties
• It is an inhibitor of RNase

Specifications

• CAS: 50-01-1
• Melting Point: 175°C to 190°C
• Color: White
• Molecular Formula: CH6ClN3
• Linear Formula: CH5N3·HCl
• MDL Number: MFCD00013026
• Quantity: 250 g
• Synonym: guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
• Solubility Information: Soluble in (6M aq soln): Relatively Clear to Cloudy Yellow Solution with Sediment on Standing.
• InChI Key: PJJJBBJSCAKJQF-UHFFFAOYSA-N
• SMILES: C(=N)(N)N.Cl
• IUPAC Name: guanidine;hydrochloride
• Molecular Weight (g/mol): 95.53
• PubChem CID: 5742
• ChEBI: CHEBI:32735
• Formula Weight: 95.53
• Grade: Practical
• Physical Form: Powder
• Chemical Name or Material: GUANIDINE HYDROCHLORIDE

Safety and Handling

Product Identifier

• Guanidine Hydrochloride, practical grade

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.

Precautionary Statement

• P101-If medical advice is needed, have product container or label at hand.
• P102-Keep out of reach of children.
• P103-Read label before use.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P321-Specific treatment (see on this label).
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : Guanidine Hydrochloride