GTPBP4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16832314	Proteintech 13897-1-AP-20UL	20 μL
16822314	Proteintech 13897-1-AP-150UL	150 μL

Description

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. ′Active′ in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

Specifications

• Antigen: GTPBP4
• Applications: Immunofluorescence, Immunoprecipitation, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human
• Gene Accession No.: Q99ME9, Q9BZE4
• Gene ID (Entrez): 23560, 69237
• Immunogen: GTPBP4 Fusion Protein Ag4859
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GTPBP4

• Concentration: 0.24 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CRFG, GTP binding protein 4, GTP binding protein NGB, GTPBP4, NGB, NOG1
• Gene Symbols: Gtpbp4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody