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GTF3A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA552497

Product Code. 15710451

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Description

Description

Immunogen sequence: KRKDYLKQHM KTHAPERDVC RCPREGCGRT YTTVFNLQSH ILSFHEESRP FVCEHAGCGK TFAMKQSLTR HAVVHDPDKK KMKLKVKKSR EKRSLASHLS GYIPPKRKQG QGLSLCQNGE SPNCVEDKML STV Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 77%.

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GTF3A
Polyclonal
Unconjugated
GTF3A
AP2; general transcription factor IIIA; GTF3A; TF3A; TFIIIA; Transcription factor IIIA
Rabbit
Antigen affinity chromatography
RUO
2971
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry, Immunohistochemistry
Lot-Specific
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q92664
GTF3A
Recombinant protein corresponding to Human GTF3A
100 μL
Primary
Human
Antibody
IgG
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