GSTM4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16816504	Proteintech 16766-1-AP-20UL	20 μL
16806504	Proteintech 16766-1-AP-150UL	150 μL

Description

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual′s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.

Specifications

• Antigen: GSTM4
• Applications: Immunofluorescence, Western Blot, Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: Q03013
• Gene ID (Entrez): 14865, 2948, 499689
• Immunogen: GSTM4 Fusion Protein Ag10340
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GSTM4

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: glutathione S transferase mu 4, GST class mu 4, GST Mu2, GSTM4, GSTM4 4, GTM4
• Gene Symbols: Gstm4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody