GSK484 hydrochloride, MedChemExpress

Product Code. 16462596

Brand: Medchem Express HY100514

Description

MedChemExpress GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.

GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.

Specifications

• Chemical Name or Material: GSK484 hydrochloride
• CAS: 1652591-81-5
• Color: Light Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₂₇H₃₂ClN₅O₃
• Quantity: 25 mg
• Solubility Information: DMSO : 125 mg/mL (245.08 mM; Need ultrasonic) ∣H2O : 50 mg/mL (98.03 mM; Need ultrasonic)
• SMILES: O=C(N1C[C@H](N)[C@H](O)CC1)C2=CC(OC)=C3C(N=C(C(N4CC5CC5)=CC6=C4C=CC=C6)N3C)=C2.[H]Cl
• Molecular Weight (g/mol): 510.03
• Formula Weight: 510.03
• Percent Purity: 97.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only