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GSK481, MedChemExpress

Product Code. 16499476
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16499476 50 mg 50mg
16489995 2 mg 2mg
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16474236 100 mg 100mg
16415537 5 mg 5mg
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Product Code. 16499476 Supplier Medchem Express Supplier No. HY100131

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Description

MedChemExpress GSK481 is a highly potent, selective, and specific receptor interacting protein 1 (RIP1) kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 (IC50=2.8 nM). GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM.

GSK481 is a highly potent, selective, and specific receptor interacting protein 1 (RIP1) kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 (IC50=2.8 nM). GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM.

Specifications

Chemical Name or Material GSK481
CAS 1622849-58-4
Color Brown
Purity Grade Notes Research
Molecular Formula C21H19N3O4
Quantity 50 mg
Solubility Information DMSO : ≥ 35 mg/mL (92.74 mM)
SMILES O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@H]3COC4=CC=CC=C4N(C)C3=O
Molecular Weight (g/mol) 377.39
Formula Weight 377.39
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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