GSK3B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA595845

Product Code. 16508691

Description

Immunogen sequence: LPNGRDTPAL FNFTTQELSS NPPLATILIP PHARIQAAAS TPTNATAASD ANTGDRGQTN NAASASASNS T

GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.

Specifications

• Antigen: GSK3B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GSK3B
• Gene Alias: 7330414F15Rik, 8430431H08Rik, C86142, EC 2.7.11.26, FA, Factor A, fb68h05, fk80d11, glycogen synthase kinase 3, glycogen synthase kinase 3 beta, glycogen synthase kinase 3 beta L homeolog, glycogen synthase kinase 3 beta variant 1, glycogen synthase kinase 3 beta variant 2, glycogen synthase kinase 3 beta variant 3, glycogen synthase kinase 3 beta variant 4, glycogen synthase kinase 3 beta variant 5, glycogen synthase kinase 3 beta, genome duplicate a, glycogen synthase kinase-3 beta, glycogen synthase kinase-3 beta splice variant X1, glycogen synthase kinase-3 beta splice variant X2, glycogen synthase kinase-3 beta splice variant X3, GSK 3 beta, GSK 3B, gsk3, GSK-3, GSK3 beta, GSK-3 beta, GSK-3 beta GSK3B, GSK-3[b], Gsk3b, GSK-3b, gsk3b.L, gsk3ba, gsk3beta, GSK-3beta, gsk3-beta, GSK3beta isoform, intracellular kinase, pp37, serine/threonine-protein kinase GSK3B, wu:fb68h05, wu:fk80d11, XELAEV_180112401mg, xgsk-3, Xgsk-3 protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2932, 56637, 84027
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.77 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
• Gene Accession No.: P18266, P49841, Q9WV60
• Gene Symbols: GSK3B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of GSK3&beta, (NP_0011396281)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG