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  6. GSK2194069, MedChemExpress

GSK2194069, MedChemExpress

Product Code. 16491327
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Product Code. 16491327 Supplier Medchem Express Supplier No. HY12325

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Description

MedChemExpress GSK2194069 is a potent inhibitor of β-ketoyl reductase (KR) of fatty acid synthase (FAS), with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively.

GSK2194069 is a potent inhibitor of β-ketoyl reductase (KR) of fatty acid synthase (FAS), with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively.

Specifications

Chemical Name or Material GSK2194069
Physical Form Solid
CAS 1332331-08-4
Color Earth Yellow
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C25H24N4O3
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 100 mg/mL (233.38 mM)
SMILES O=C(N1C[C@H](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6
Molecular Weight (g/mol) 428.48
Formula Weight 428.48
Percent Purity 99.67%
Grade Research
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Research purposes only

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