ACROBiosystems Human KIR2DL3 / CD158b2 Protein, Fc Tag

Product Code. 16437819

Brand: ACROBiosystems KI3H52571mg

Description

Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.2 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

• Accession Number: NP_056952.2
• Molecular Weight (g/mol): 51.2 kDa
• Quantity: 1 mg
• Source: Human KIR2DL3, Fc Tag (KI3-H5257) is expressed from human 293 cells (HEK293). It contains AA His 22 - His 245 (Accession # NP_056952.2).
• Immunogen: His 22 - His 245
• Storage Requirements: -20°C
• Gene Alias: KIR2DL3,CD158B2,KIRCL23,NKAT2,KIR-023 GB,NKAT2a,NKAT2b,NKAT-2,CD158 B2,GL183,KIR-023 GB,KIR-K7b,KIR-K7c,KIRCL23,NKAT,p58
• Common Name: KIR2DL3
• Conjugate: Unconjugated
• Species: Human
• Protein Tag: Fc Tag
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Endotoxin Level: Less than 1.0 EU / μg by the LAL method.
• Expression System: HEK293
• Form: Powder
• Protein Subtype: Bio-Markers and CD Antigens
• Purity or Quality Grade: >95% as determined by SDS-PAGE