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STEMCELL Technologies GSA 10

Product Code. 17150182
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 17150182

Brand: STEMCELL Technologies 73174

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This item is not returnable. View return policy

Description

Hedgehog pathway activator; Activates Smoothened (SMO)

  • GSA 10 is an agonist of Smoothened (SMO), a cell surface receptor and mediator of the hedgehog signaling pathway
  • It is a quinolinecarboxamide derivative that binds in a distinct binding pocket from cyclopamine
  • GSA10 is active at an EC50 of 1.2 μM in an alkaline phosphatase-based mouse mesenchymal cell line (C3H10T1/2) differentiation assay (Gorojankina et al.)
  • Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts (Gorojankina et al.)

Specifications

CAS 300833-95-8
Quantity 50 mg
Molecular Formula C26H30N2O5
Purity ≥95%
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