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GRPR Polyclonal Antibody, Invitrogen™

Product Code. 13401177
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
13401177 100 μL 100µL
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Product Code. 13401177 Supplier Invitrogen Supplier No. PA527073

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLaS3, Molt-4, mouse pancreas, mouse brain, rat brain, rat pancreas. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRPR
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene GRPR
Gene Accession No. P21729, P30550, P52500
Gene Alias BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R
Gene Symbols GRPR
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region within amino acids 200 and 294 of Human GRPR
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14829, 24938, 2925
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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