Invitrogen™ GRPEL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553747

Product Code. 15761681

Description

Immunogen sequence: EPEDQKLTLE KVFRGLLLLE AKLKSVFAKH GLEKLTPIGD KYDPHEHELI CHVPAGVGVQ PGTVALVRQD GYKLHGRTIR LARVEVAVES Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.

GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.

Specifications

• Antigen: GRPEL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRPEL2
• Gene Alias: actin filament-associated protein 1-like 1; Afap1l1; AFAP1-like protein 1; GrpE like 2, mitochondrial; grpE protein homolog 2, mitochondrial; Grpel2; GrpE-like 2, mitochondrial; Mt-GrpE#2; Mt-grpel2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 134266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TAA5
• Gene Symbols: GRPEL2
• Immunogen: Recombinant protein corresponding to Human GRPEL2. Recombinant protein control fragment (Product #RP-91014).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG