Invitrogen™ Growth Hormone Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA185519

Product Code. 11503681

Description

Sheep anti Human growth hormone antibody recognizes human growth hormone. Growth hormone is a small peptide hormone released by the anterior pituitary under the control of the hypothalamus. It acts to control body growth and metabolic activity.

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

Specifications

• Antigen: Growth Hormone
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gh1
• Gene Alias: dog growth hormone; GH; Gh1; GHB1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B1; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; pituitary growth hormone; rHGH; RNGHGP; Somatotropin
• Host Species: Sheep
• Quantity: 250 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Radioimmune Assays (RIA)
• Concentration: Conc. Not Determined
• Formulation: Whole serum with <0.1% sodium azide
• Gene Accession No.: P01241
• Gene Symbols: Gh1
• Immunogen: Purified native human growth hormone.
• Regulatory Status: RUO
• Gene ID (Entrez): 2688
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid