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Invitrogen™ Human Growth Hormone, Recombinant Protein
Recombinant Protein
Brand: Invitrogen™ RP10912
This item is not returnable.
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Description
Human Growth Hormone Recombinant Protein, RP-10912, from Invitrogen.
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature. This is a recombinant protein suitable for use as a control in ELISA and Western blot applications. This protein is reported to have the additional biological activity: ED50 as determined by a cell proliferation assay using rat lymphona Nb2-11 cells. Endotoxin level is less than 0.1ng/ug. Store lyophilized product desiccated at -20°C. Upon reconstitution, store at 4°C for 2-7 days or aliquot and store at -20°C. For long term storage add either HSA or BSA to 0.1%. Avoid repeated freeze/thaw cycles. Reconstitute using distilled water to a concentration not less than 100 ug/ml.Specifications
P01241 | |
Control | |
2688 | |
500μg | |
-20°C, Avoid Freeze/Thaw Cycles | |
HGH | |
GH1 | |
Unconjugated | |
E. coli | |
Lyophilized | |
purified |
10mg/mL | |
protein with no preservative | |
Human Growth Hormone | |
E. coli | |
RUO | |
Human Growth Hormone | |
Human | |
Hu | |
Recombinant | |
Recombinant |