missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18745666

Tocris Bioscience™ GRL 0617
GREENER_CHOICE

Product Code. 18745666
Change view
Click to view available options
Quantity:
5 mg
Unit Size:
5mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18745666 5 mg 5mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 18745666 Supplier Tocris Bioscience™ Supplier No. 7280/5

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Coronavirus PLpro inhibitor

GRL 0617 is a coronavirus papain-like protease (Plpro) inhibitor (IC50 values are 0.6 and 0.8 μM for SARS-COV and SARS-CoV-2 PLpro, respectively). Inhibits deubiquitination activity of SARS-CoV PLpro. Displays no inhibition of human deubiquitinating enzymes. Improves cell viability following SARS-CoV infection. Inhibits SARS-CoV-2 viral replication and induces antiviral immune signaling pathways following SARS-CoV-2 infection in CaCo-2 cells.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 5-Amino-2-methyl-N-[(1 R)-1-(1-naphthalenyl)ethyl]benzamide
CAS 1093070-16-6
Quantity 5 mg
Target Papain-like Protease Inhibitors
Molecular Formula C20H20N2O
Purity 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.