Invitrogen™ GRK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA581896

Product Code. 16358864

Description

Immunogen sequence: YEAVNADTDK IEARKRAKNK QLGHEEDYAL GKDCIMHGYM LKLGNPFLTQ WQRRYFYLFP NRLEWRGEGE SRQNLLTMEQ ILSVEETQIK DKKCILFRIK GGKQFVLQCE SDPEFVQWKK ELNETFKEAQ RLLRRAPKFL NKPRS Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 89%.

ADRBK2, or adrenergic beta receptor kinase 2 is a serine/threonine kinase that is thought to act as a regulator of receptor function. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Specifications

• Antigen: GRK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRK3
• Gene Alias: 4833444A01Rik; ADRBK2; Adrbk-2; adrenergic receptor kinase, beta 2; adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase); adrenergic, beta, receptor kinase 2; AI851927; AW551196; BARK2; Bark-2; beta ARK2; beta-adrenergic receptor kinase 2; Beta-ARK-2; G protein-coupled receptor kinase 3; G-protein-coupled receptor kinase 3; Grk3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 157
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P35626
• Gene Symbols: GRK3
• Immunogen: Recombinant protein corresponding to Human GRK3. Recombinant protein control fragment (Product #RP-91358).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG