Invitrogen™ GRASP1 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142111

Product Code. 17808272

Description

Additional Information: This antibody is expected to recognize both reported isoforms (as represented by NP_064522.3; NP_997555.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000. Preliminary analysis showed no signal in Western Blot.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).

Specifications

• Antigen: GRASP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIPAP1
• Gene Alias: 30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 56850
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q4V328
• Gene Symbols: GRIPAP1
• Immunogen: Peptide with sequence LREQTTGLAAELQ-C (aa 359-371).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG