Invitrogen™ GRAP Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA517953

Product Code. 11345923

Description

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Specifications

• Antigen: GRAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRAP
• Gene Alias: 8430435N19Rik; BB233594; GRAP; GRB2 related adaptor protein; GRB2-related adapter protein; GRB2-related adaptor protein; growth factor receptor-bound protein 2-related adaptor protein; MGC64880
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10750
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13588
• Gene Symbols: GRAP
• Immunogen: Synthetic peptide sequence (GFFPRSYVQPVHL) corresponding to the C-terminus amino acids of GRAP (aa 205-217).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG