Invitrogen™ GRAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5111238

Product Code. 17179153

Description

Immunogen sequence: ELVDFYRTTT IAKKRQIFLR DEEPLLKSPG ACFAQAQFDF SAQDPSQLSF RRGDIIEVLE RPDPHWWRGR SCGRVGFFPR SYVQPVHL Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 84%.

This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Specifications

• Antigen: GRAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRAP
• Gene Alias: 8430435N19Rik; BB233594; GRAP; GRB2 related adaptor protein; GRB2-related adapter protein; GRB2-related adaptor protein; growth factor receptor-bound protein 2-related adaptor protein; MGC64880
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10750
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13588
• Gene Symbols: GRAP
• Immunogen: Recombinant Protein corresonding to Human GRAP. Recombinant protein control fragment (Product #RP-96521).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG