Invitrogen™ GRAMD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA569331

Product Code. 15837743

Description

This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%.

Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner. Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE).

Specifications

• Antigen: GRAMD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRAMD2A
• Gene Alias: BC064463; GRAM domain containing 2; GRAM domain containing 2A; GRAM domain-containing protein 2; GRAM domain-containing protein 2; GRAM domain-containing protein 2A; GRAM domain-containing protein 2A; GRAMD2; GRAMD2A; RGD1564007
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 196996
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8IUY3
• Gene Symbols: GRAMD2A
• Immunogen: synthetic peptide directed towards the middle region of human GRAMD2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG