Invitrogen™ GRAF Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583259

Product Code. 16380215

Description

Immunogen sequence: RSSLHAVFSL LVNFVPCHPN LHLLFDRPEE AVHEDSSTPF RKAKALYACK AEHDSELSFT AGTVFDNVHP SQEPGWLE Highest antigen sequence indentity to the following orthologs: Rat - 56%, Mouse - 96%.

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: GRAF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGAP26
• Gene Alias: 1810044B20Rik; 2610010G17Rik; 4933432P15Rik; AI853435; Arhgap26; FLJ42530; GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); Kiaa0621; mKIAA0621; oligophrenin-1-like protein; OPHN1L; OPHN1L1; Rho GTPase activating protein 26; rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23092
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UNA1
• Gene Symbols: ARHGAP26
• Immunogen: Recombinant protein corresponding to Human ARHGAP26. Recombinant protein control fragment (Product #RP-102650).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG