Invitrogen™ GPR37 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA513413

Product Code. 10526100

Description

GPR37 Polyclonal Antibody for Western Blot, IHC (P)

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.

Specifications

• Antigen: GPR37
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR37
• Gene Alias: AI848630; EDNRBL; endothelin B receptor-like protein 1; ETBR-LP-1; G protein-coupled receptor 37; G protein-coupled receptor 37 (endothelin receptor type B-like); Gpcr/cns1; Gpr37; G-protein coupled receptor 37; G-protein coupled receptor CNS1; hET(B)R-LP; Het-b-r-lp; Pael receptor; PAELR; Pael-R; parkin-associated endothelin B-like receptor; Parkin-associated endothelin receptor-like receptor; probable G-protein coupled receptor 37; prosaposin receptor GPR37
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 14763, 2861
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: O15354, Q9QY42
• Gene Symbols: GPR37
• Immunogen: KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human Pael-R (GPR37).
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG