Invitrogen™ GPR143 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551984

Product Code. 15719940

Description

Immunogen sequence: CSLGFQSPRK EIQWESLTTS AAEGAHPSPL MPHENPASGK VSQVGGQTSD EALSMLSEGS DASTIEIHTA SESCNKNEGD PALPT Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 55%.

Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.

Specifications

• Antigen: GPR143
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR143
• Gene Alias: G protein-coupled receptor 143; GPR143; G-protein coupled receptor 143; homolog of human ocular albinism 1 (Nettleship-Falls); MOA1; NYS6; OA1; ocular albinism 1; ocular albinism type 1 protein; Ocular albinism type 1 protein homolog; RGD1565799
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4935
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P51810
• Gene Symbols: GPR143
• Immunogen: Recombinant protein corresponding to Human GPR143. Recombinant protein control fragment (Product #RP-92329).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG