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Description
Immunogen sequence: CSLGFQSPRK EIQWESLTTS AAEGAHPSPL MPHENPASGK VSQVGGQTSD EALSMLSEGS DASTIEIHTA SESCNKNEGD PALPT Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 55%.
Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.
Specifications
Specifications
| Antigen | GPR143 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | GPR143 |
| Gene Accession No. | P51810 |
| Gene Alias | G protein-coupled receptor 143; GPR143; G-protein coupled receptor 143; homolog of human ocular albinism 1 (Nettleship-Falls); MOA1; NYS6; OA1; ocular albinism 1; ocular albinism type 1 protein; Ocular albinism type 1 protein homolog; RGD1565799 |
| Gene Symbols | GPR143 |
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Product Title
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