Invitrogen™ GPR123 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575823

Product Code. 15992345

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR123 (G protein-coupled receptor 123) is a 1,279 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Existing as two alternatively spliced isoforms, GPR123 functions as an orphan receptor that is expressed in adult and fetal brain, and in adult spinal cord. The gene encoding GPR123 maps to human chromosome 10q26.3 and mouse chromosome 7 F4.

Specifications

• Antigen: GPR123
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADGRA1
• Gene Alias: 2900059M17Rik; Adgra1; Adhesion G protein-coupled receptor A1; D7Ertd680e; G protein-coupled receptor 123; GPR123; G-protein coupled receptor 123; KIAA1828; probable G-protein coupled receptor 123
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 309097, 52389, 84435
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86SQ6, Q8C4G9
• Gene Symbols: ADGRA1
• Immunogen: Synthetic peptide corresponding to residues in Human GPR123.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG