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Invitrogen™ GPR112 Polyclonal Antibody
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Product Code. 16664135
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Quantity:
100 μL
Unit Size:
100µL
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16664135 100 μL 100µL
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Product Code. 16664135 Supplier Invitrogen™ Supplier No. PA599890

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GPR112.

G protein-coupled receptors(GPRs or GPCRs), also known asseven transmembrane receptors, heptahelical receptors or 7TMreceptors, aremembers of the largest protein family and play a role in many differentstimulus-response pathways. G protein-coupled receptors mediate extracellularsignals into intracellularsignals(G protein activation). Theyrespond to awide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usuallyintegralseven passmembrane proteins with some conserved amino acid regions. GPR112 (G protein-coupled receptor 112) is a 3,080 amino acid multi-pass membrane protein that belongsto the G-protein coupled receptor 2 family and LN-TM7 subfamily. Localizing to cell membrane, GPR112 is highly expressed in normal enterochromaffin cells, aswell as neuroendocrine and primarylivercarcinoma. GPR112 contains one GPS domain andmayfunction as an orphan receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR112
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ADGRG4
Gene Accession No. Q8IZF6
Gene Alias ADGRG4; adhesion G protein-coupled receptor G4; adhesion G-protein coupled receptor G4; G protein-coupled receptor 112; Gm367; GPR112; G-protein coupled receptor 112; PGR17; probable G-protein coupled receptor 112; RP1-299I16
Gene Symbols ADGRG4
Host Species Rabbit
Immunogen A synthesized peptide derived from human ADGRG4(Accession Q8IZF6), corresponding to amino acid residues T3047-P3080.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 139378
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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