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Invitrogen™ GPIP137 Polyclonal Antibody

Description
Immunogen sequence: LWDLLEGKEK PVCGTTYKVL KEIVERVFQS NYFDSTHNHQ NGLCEEEEAA SAPAVEDQVP EAEPEPAEEY TEQSEVESTE YVNRQFMAET QFTSGEKEQV DEWTVETVEV VNSLQQQPQA ASPSVPEPHS LTPVAQ Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.
Specifications
Specifications
| Antigen | GPIP137 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Caprin1 |
| Gene Accession No. | Q14444 |
| Gene Alias | activation/proliferation-associated protein 1; AL022980; caprin 1; Caprin1; caprin-1; cell cycle associated protein 1; cell cycle-associated protein 1; cytop; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; G5E5; GPI p137; GPI-anchored membrane protein 1; GPI-anchored protein p137; Gpiap; GPIAP1; Gpip137; GPI-p137; GRIP137; M11S1; Membrane component chromosome 11 surface marker 1; membrane component, chromosome 11, surface marker 1; Mmgpip137; P137; p137GPI; RNA granule protein 105; Rng105 |
| Gene Symbols | Caprin1 |
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