Invitrogen™ GPI Monoclonal Antibody (K94005_19C2), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA555714

Product Code. 30209291

Description

Sequence of this protein is as follows: MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP EVNKVLDKMK SFCQRVRSGD WKGYTGKTIT DVINIGIGGS DLGPLMVTEA LKPYSSGGPR VWYVSNIDGT HIAKTLAQLN PESSLFIIAS KTFTTQETIT NAETAKEWFL QAAKDPSAVA KHFVALSTNT TKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DNFEQLLSGA HWMDQHFRTT PLEKNAPVLL ALLGIWYINC FGCETHAMLP YDQYLHRFAA YFQQGDMESN GKYITKSGTR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL HHKILLANFL AQTEALMRGK STEEARKELQ AAGKSPEDLE RLLPHKVFEG NRPTNSIVFT KLTPFMLGAL VAMYEHKIFV QGIIWDINSF DQWGVELGKQ LAKKIEPELD GSAQVTSHDA STNGLINFIK QQREARVQ

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Specifications

• Antigen: GPI
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: P06744
• Gene Symbols: GPI
• Immunogen: Recombinant human GPI (immunogen range is 1-558).
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunoprecipitation, Western Blot
• Clone: K94005_19C2
• Conjugate: Unconjugated
• Gene: GPI
• Gene Alias: Amf; Autocrine motility factor; glucose phosphate isomerase; glucose phosphate isomerase 1; glucose phosphate isomerase 1 complex; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; glucose-6-phosphate isomerase; glucose-6-phosphate isomerase {ECO:0000250; GNPI; Gpi; GPI {ECO:0000250; gpi {ECO:0000312; GPI1; Gpi-1; Gpi-1r; Gpi1-r; Gpi1s; Gpi-1s; Gpi1-s; Gpi-1t; Gpi1-t; GPI-GlcNAc transferase complex subunit GPI1; hexose monophosphate isomerase; hexosephosphate isomerase; maturation factor; MF; Neuroleukin; neuroleukin {ECO:0000250; NK; NK/GPI; Nlk; NLK {ECO:0000250; Org; oxoisomerase; PGI; PGI {ECO:0000250; Phi; PHI {ECO:0000250; phosphatidylinositol N-acetylglucosaminyltransferase; Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1; Phosphoglucose isomerase; phosphoglucose isomerase {ECO:0000250; phosphohexomutase; phosphohexose isomerase; phosphohexose isomerase {ECO:0000250; phosphosaccharomutase; RGD:2727}; SA36; SA-36; sperm antigen; sperm antigen 36; sperm antigen-36; UniProtKB:P06745}; YGR216C
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2821
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid